Welcome to qPTM
Post-translational modifications (PTMs) are critical molecular mechanisms that regulate the protein functions temporally and spatially in almost all organisms especially in human. Besides the modification sites, the quantifications of the dynamic modification events under different states/conditions are fundamental for understanding the phosphorylation signalling. With the rapid development of high-throughput proteomics technologies, massive quantitative PTM proteome datasets have been generated. Thus, a comprehensive one-stop data resource for surfing the big data will be very useful to the community.
Previously, we developed the qPhos database to host the quantitative phosphoproteome data, here we update it to qPTM database for 10 types of PTMs including phosphorylation, acetylation, ubiquitylation, glycosylation, methylation, SUMOylation, butyrylation, succinylation, crotonylation and hydroxyisobutyrylation. In total, 4,544,734 quantification events of 10 PTMs for 296,915 sites in 19,641 proteins under 661 conditions are collected and integrated in the database.